Stan Van Uum, MD,PhD
Dr. Stan Van Uum is an Assistant Professor in the divisions of Clinical Pharmacology and Endocrinology and Metabolism. He completed his undergraduate and graduate training in Internal Medicine in 1997, followed by a Fellowship in Endocrinology and Metabolism (2001), all at the University of Nijmegen in The Netherlands. He then completed his PhD in Medicine on the role of cortisol metabolism in hypertension (2003, University of Nijmegen, Supervisor: Dr. Jacques Lenders).
Between 2002 and summer 2003, he worked as an Internist at the Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon. In summer 2003, he joined the Department of Medicine at the University of Western Ontario.
Dr. Van Uum is interested in the role of hormones, particularly steroid hormones, in health and disease. These studies include consequences of drug-induced hypogonadism, and the measurement of steroid hormones in hair of the head, for which he has received funding from the Physician's Services Incorporation. Further, he is collaborating in studies on the effect of genetic variants in adenylyl cyclase on cardiovascular risk factors (including hypertension, obesity and metabolic control). His research activities are embedded within the Division of Clinical Pharmacology.
His clinical practice is located at St. Joseph's Health Centre and is focused on endocrinology, with a particular interest in pituitary and adrenal diseases, and secondary hypertension. Stan Van Uum is actively involved in teaching in relation to these areas.

Publications
2000  2001  2002  2003  2004
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E.M. Roumen-Klappe, M. den Heijer, S.H. van Uum, J. van der Ven-Jongekrijg, F. van der Graaf, H. Wollersheim. Inflammatory response in the acute phase of deep vein thrombosis. J Vasc Surg. 2002 Apr;35(4):701-6. [Pubmed]

S.H.M. van Uum, A.R.M.M. Hermus, C.G.J. Sweep, B.R Walker, H.A. Ross, P.W. de Leeuw and J.W.M. Lenders Short-term infusion of cortisol in the brachial artery, with or without inhibition of 11b-hydroxysteroid dehydrogenase, does not alter forearm vascular resistance in normotensive and hypertensive subjects Eur J Clin Invest 2002 Dec;32(12):874-81. [Pubmed]

Stan H.M. van Uum, Alphons J.H.M. Houben, Ad R.M.M. Hermus, Abraham A. Kroon, Brian R Walker, C.G.J. (Fred) Sweep, Paul Smits, Peter W. de Leeuw and Jacques W.M. Lenders Acute intrarenal administration of cortisol has no effect on renal blood flow in hypertensive individuals J Hypertension 2002, Nov; 20 (11):2276-2283. [Pubmed]

Stan HM van Uum, Brian R Walker, Ad RMM Hermus, CGJ (Fred) Sweep, Paul Smits, Peter W de Leeuw and Jacques WM Lenders, Effect of glycyrrhetinic acid on 11-hydroxysteroid dehydrogenase activity in normotensive and hypertensive subjects, Clinical Science 2002 Feb;102(2):203-11 [Pubmed]